Respiratory

Rebordosa C, Farkas DK, Montonen J, Laugesen K, Voss F, Aguado J, Bothner U, Rothman KJ, Zint K, Mines DI, Ehrenstein V. Cardiovascular events and all-cause mortality in patients with chronic obstructive pulmonary disease using olodaterol and other long-acting beta2-agonists. Pharmacoepidemiol Drug Saf. 2022 Aug;31(8):827-39. doi: 10.1002/pds.5432


PURPOSE: We examined the effect of olodaterol on the risk of myocardial ischaemia, cardiac arrhythmia, and all-cause mortality compared with use of other long-acting beta2-agonists (LABAs). Channelling bias was also explored.

Bell CF, Meyers J, Ajmera M. Incremental healthcare costs of Eosinophilic Granulomatosis with Polyangiitis (EGPA) compared to asthma: retrospective analysis of commercial claims data in the United States (US). Poster presented at the 2021 Virtual American College of Rheumatology (ACR) Convergence; November 6, 2021. [abstract] Arthritis Rheumatol. 2021; 73(Suppl 10).


Rivero-Ferrer E, Olesen M, Plana E, Aguado J, Saigi-Morgui N, Rubino A, Daoud SZ, Lei A, Perez-Gutthann S, Schink S, Kristiansen NS, Hallas J, Pottegard A, Rebordosa C. Characteristics of new users of aclidinium bromide, aclidinium/formoterol, and other COPD medications in the United Kingdom, Denmark, and Germany. Clin Drug Invest. 2022 Apr;42(4):319-31. doi: 10.1007/s40261-022-01120-2


Rebordosa C, Plana E, Rubino A, Aguado J, Lei A, Daoud S, Saigi-Morgui N, Perez-Gutthann S, Rivero-Ferrer E. A cohort study to evaluate the risk of hospitalisation for congestive heart failure associated with the use of aclidinium and other chronic obstructive pulmonary disease medications in the UK Clinical Practice Research Datalink. Int J Chron Obstruct Pulmon Dis. 2021 May 31;16:1461-75. doi: 10.2147/COPD.S301624


BACKGROUND: The long-acting anticholinergic (LAMA) aclidinium was approved in Europe in 2012 to relieve symptoms in adults with chronic obstructive pulmonary disease (COPD). A Post-Authorisation Safety Study (PASS) was initiated to assess potential cardiovascular safety concerns for aclidinium.

Simpson EL, de Bruin-Weller M, Bansal A, Chen Z, Nelson L, Whalley D, Prescilla R, Guillemin I, Delevry D. Definition of clinically meaningful within-patient changes in POEM and CDLQI in children 6 to 11 years of age with severe atopic dermatitis. Dermatol Ther. 2021 Aug;11(4):1415-22. doi: 10.1007/s13555-021-00543-7


Jacquemin B, Sunyer J, Forsberg B, Aguilera I, Briggs D, Garcia-Esteban R, Gotschi T, Heinrich J, Jarvholm B, Jarvis D, Vienneau D, Kunzli N. Home outdoor NO2 and new onset of self-reported asthma in adults. Epidemiology. 2009 Jan;20(1):119-26. doi: 10.1097/EDE.0b013e3181886e76


BACKGROUND: Few studies have investigated new onset of asthma in adults in relation to air pollution. The aim of this study is to investigate the association between modeled background levels of traffic-related air pollution at the subjects' home addresses and self-reported asthma incidence in a European adult population.

Kunzli N, Bridevaux PO, Liu LJ, Garcia-Esteban R, Schindler C, Gerbase MW, Sunyer J, Keidel D, Rochat T, Swiss Cohort Study on Air Pollution and Lung Diseases in Adults. Traffic-related air pollution correlates with adult-onset asthma among never-smokers. Thorax. 2009 Aug;64(8):664-70. doi: 10.1136/thx.2008.110031


Jacquemin B, Sunyer J, Forsberg B, Aguilera I, Buoso L, Briggs D, de Marco R, Garcia-Esteban R, Henrich J, Jarvis D, Maldonado JA, Payo F, Rage E, Vienneau D, Kunzli N. Association between modelled traffic-related air pollution and asthma score in the ECRHS. Eur Respir J. 2009 Oct;34(4):834-42. doi: 10.1183/09031936.00138208


Anto JM, Sunyer J, Basagana X, Garcia‐Esteban R, Cerveri I, de Marco R, Heinrich J, Janson C, Jarvis D, Kogevinas M, Kuenzli N, Leynaert B, Svanes C, Wjst M, Gislason T, Burney P. Risk factors of new-onset asthma in adults: a population-based international cohort study. Allergy. 2010 Aug;65(8):1021-30. doi: 10.1111/j.1398-9995.2009.02301.x


BACKGROUND: The occurrence of new‐onset asthma during adulthood is common, but there is insufficient understanding of its determinants including the role of atopy.

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