Respiratory

Morales E, Bustamante M, Vilahur N, Escaramis G, Montfort M, de Cid R, Garcia-Esteban R, Torrent M, Estivill X, Grimalt JO, Sunyer J. DNA hypomethylation at ALOX12 is associated with persistent wheezing in childhood. Am J Respir Crit Care Med. 2012 May 1;185(9):937-43. doi: 10.1164/rccm.201105-0870OC


RATIONALE: Epigenetic changes may play a role in the occurrence of asthma-related phenotypes.

Sunyer J, Garcia-Esteban R, Castilla AM, Aurrekoetxea JJ, Iniguez C, Tardon A, Espada M, Lertxundi A, Chatzi L, Rebagliato M, Kogevinas M, INMA Project. Exposure to second-hand smoke and reproductive outcomes depending on maternal asthma. Eur Respir J. 2012 Aug;40(2):371-6. doi: 10.1183/09031936.00091411


Leynaert B, Sunyer J, Garcia-Esteban R, Svanes C, Jarvis D, Cerveri I, Dratva J, Gislason T, Heinrich J, Janson C, Kuenzli N, de Marco R, Omenaas E, Raherison C, Gomez Real F, Wjst M, Zemp E, Zureik M, Burney PG, Anto JM, Neukirch F. Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort. Thorax. 2012 Jul;67(7):625-31. doi: 10.1136/thoraxjnl-2011-201249


BACKGROUND: Although women with severe non-allergic asthma may represent a substantial proportion of adults with asthma in clinical practice, gender differences in the incidence of allergic and non-allergic asthma have been little investigated in the general population.

Rebordosa C, Rubino A, Witzleb AJ, Olesen M, Plana E, Aguado J, Saigi N, Daoud SZ, Lei A, Perez-Gutthann S, Schink T, Kristiansen NS, Pottegard A, Rivero-Ferrer E. Characteristics of new users of aclidinium, aclidinium/formoterol, and other COPD medications in three European countries. Poster presented at the 2020 Virtual ERS International Congress; October 2020. [abstract] Eur Respir J. 2020 Oct 28; 56(Suppl 64):2071. doi: 10.1183/13993003.congress-2020.2072


BACKGROUND: Use of aclidinium bromide (AB) and aclidinium/formoterol (AB/FF) in the real world is not fully characterized in Europe. Aim: To describe characteristics of new users of AB, AB/FF, and other COPD medications in the United Kingdom (UK), Denmark, and Germany.

Davis A, Jiang J, Talbird S, Turpin RS, Mellott CE, Boules M, Wojtowicz AM, Fan T. Pharmacological costs for the treatment of eosinophilic esophagitis in the USA. Poster presented at the 2021 Virtual Digestive Disease Week (DDW) Conference; May 21, 2021. Previously presented at the 2021 AMCP Conference.


Davis AE, Jiang J, Talbird SE, Turpin R, Mellott CE, Boules M, Wojtowicz AM, Fan T. Pharmacological costs for the treatment of eosinophilic esophagitis in the USA. Poster presented at the 2021 Virtual AMCP; April 2021.


Crowe HM, Wise LA, Wesselink AK, Rothman KJ, Mikkelsen EM, Sorensen HT, Walkey AJ, Hatch EE. Association of asthma diagnosis and medication use with fecundability: a prospective cohort study. Clin Epidemiol. 2020 Jun 8;12:579-87. doi: 10.2147/CLEP.S245040


Oppenheimer J, Slade DJ, Hahn BA, Zografos L, Gilsenan A, Richardson D, McSorley D, Lima R, Molfino NA, Averell CM. Real-world evidence: patient views on asthma in respiratory specialist clinics in America. Ann Allergy Asthma Immunol. 2021 Apr;126(4):385-93. doi: 10.1016/j.anai.2020.12.015


BACKGROUND: Approximately 30–50% of patients with moderate/severe asthma have inadequately controlled disease despite adherence to inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) therapy. Data on prevalence and burden of uncontrolled asthma in specialty settings is lacking.

Davidson D, Stevenson M, Llonch MV, Hsieh A, Brown TM, Slota C, Fehnel S. Development of a novel patient-reported outcome measure  symptoms and impacts of familial chylomicronemia syndrome. J Clin Lipidol. 2020 Jul;14(4):P571.


Abstract not available at this time.

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